Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1023081 | 0.91 | GRM5 (0.50) | GRM5KCNH2 | |
| SCHEMBL980685 | 0.80 | GRM5 (0.61) | GRM5KCNH2 | |
| SCHEMBL979991 | 0.74 | GRM5 (0.48) | GRM5KCNH2 | |
| SCHEMBL980654 | 0.74 | GRM5 (0.58) | GRM5KCNH2 | |
| SCHEMBL1020277 | 0.72 | GRM5 (0.50) | GRM5KCNH2 | |
| SCHEMBL1023078 | 0.71 | GRM5 (0.53) | GRM5KCNH2 | |
| SCHEMBL1021161 | 0.71 | GRM5 (0.53) | GRM5KCNH2 | |
| SCHEMBL983538 | 0.71 | GRM5 (0.50) | GRM5KCNH2 | |
| SCHEMBL1020958 | 0.70 | GRM5 (0.54) | GRM5KCNH2 | |
| SCHEMBL1020977 | 0.70 | GRM5 (0.63) | GRM5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670784-A1 | HETEROARYL-SUBSTITUTED IMDAZOLE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| WO-2004111040-A1 | HETEROARYL-SUBSTITUTED IMDAZOLE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-12-23 | — | — | WO | disclosed |