Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 16/20 | 0.38 |
| ▸ | F10 | P00742 | 4/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | F7 | P08709 | 2/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6028321 | 0.90 | ST14 (0.39) | ST14F2F10PRSS1F7 | |
| Acetic Acid SCHEMBL6027976 | 0.82 | F10 (0.43) | F2F10PRSS1F7 | |
| SCHEMBL6028386 | 0.81 | F10 (0.35) | F2F10PRSS1F7KLKB1 | |
| SCHEMBL6028739 | 0.79 | ST14 (0.38) | ST14F2F10PRSS1F7 | |
| Acetic Acid SCHEMBL6028736 | 0.77 | F2 (0.39) | ST14F2F10PRSS1F7 | |
| SCHEMBL6029054 | 0.77 | F10 (0.35) | F10 | |
| Acetic Acid SCHEMBL6028580 | 0.75 | F10 (0.34) | F10 | |
| SCHEMBL6029267 | 0.74 | ST14 (0.38) | ST14F2F10PRSS1F7 | |
| SCHEMBL6028373 | 0.73 | F10 (0.36) | F2F10PRSS1F7KLKB1 | |
| SCHEMBL6031646 | 0.73 | ST14 (0.39) | ST14F2F10PRSS1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706149-A2 | LIPOSOME COMPOSITION FOR DELIVERY OF THERAPEUTIC AGENTS | ALZA CORPORATION (US) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005070466-A2 | LIPOSOME COMPOSITION FOR DELIVERY OF THERAPEUTIC AGENTS | ALZA CORPORATION (US) | 2005-08-04 | — | — | WO | disclosed |
| WO-2005066137-A1 | 2,5-DIARYL-1H-IMIDAZOLE-4-CARBOXAMIDES AS NEUROKININ-3 RECEPTOR MODULATORS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM AND PERIPHERAL DISEASES | NEUROGEN CORPORATION (US) | 2005-07-21 | — | — | WO | disclosed |