SCHEMBL60294

SCHEMBL60294

C=C(CCCC#N)CC(C)C#N

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21218816 0.82 TSHR (0.33) TSHR
SCHEMBL59615 0.81 TSHR (0.38) TSHR
SCHEMBL10959155 0.80 TSHR (0.40) TSHR
SCHEMBL60459 0.78 TSHR (0.41) TSHR
SCHEMBL14434752 0.77 TSHR (0.39) TSHR
SCHEMBL11146687 0.77 TSHR (0.42) TSHR
SCHEMBL11292505 0.73 TSHR (0.38) TSHR
SCHEMBL60697 0.72 TSHR (0.32) TSHR
SCHEMBL60457 0.71 TSHR (0.39) TSHR
SCHEMBL11223701 0.71 TSHR (0.44) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5874625-A Process to hydrogenate organic nitriles to primary amines HENKEL CORPORATION (US) 1999-02-23 US claimed
WO-1998019991-A1 IMPROVED PROCESS TO HYDROGENATE ORGANIC NITRILES TO PRIMARY AMINES HENKEL CORPORATION (US) 1998-05-14 WO claimed
US-4324738-A Dinitriles and their preparation PHILLIPS PETROLEUM COMPANY (US) 1982-04-13 US claimed
US-4302604-A BY STARTING AT A REDUCED PRESSURE AND INCREASING PRESSURE DURING HYDROGENATION PHILLIPS PETROLEUM COMPANY (US) 1981-11-24 US claimed
US-4243610-A Cobalt-gold promoter for ruthenium hydrogenation catalyst as in hydrogenation of unsaturated dinitriles PHILLIPS PETROLEUM COMPANY (US) 1981-01-06 US claimed
US-4235808-A CATALYTIC HYDROGENATION TO SATURATED DIAMINE PHILLIPS PETROLEUM COMPANY (US) 1980-11-25 US claimed
US-4201632-A Separation of phenol-, cyclohexanone-, and cyclohexylbenzene-containing mixtures employing a nitrile as extraction distillation solvent PHILLIPS PETROLEUM COMPANY (US) 1980-05-06 US claimed
US-4172849-A HYDROGENATION OF UNSATURATED DINITRILES TO SATURATED DIAMINES PHILLIPS PETROLEUM COMPANY (US) 1979-10-30 US claimed
US-4152291-A FOR HYDROGENATION OF BRANCHED, OLEFINICALLY UNSATURATED, ALIPHATIC DINITRILE PHILLIPS PETROLEUM COMPANY (US) 1979-05-01 US claimed
US-4152351-A USING MANAGANESE OR LANTHANIDE ADJUVANTS ON CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1979-05-01 US claimed
US-8128808-B2 Process for hydrodesulfurization, hydrodenitrogenation, hydrofinishing, or amine production H R D CORPORATION (US) 2012-03-06 US disclosed
EP-2379678-A1 PROCESS FOR HYDRODESULFURIZATION, HYDRODENITROGENATION, HYDROFINISHING, OR AMINE PRODUCTION H R D Corporation (US) 2011-10-26 EP disclosed
US-20100294699-A1 PROCESS FOR HYDRODESULFURIZATION, HYDRODENITROGENATION, HYDROFINISHING, OR AMINE PRODUCTION H R D CORPORATION (US) 2010-11-25 US disclosed
WO-2010090811-A1 PROCESS FOR HYDRODESULFURIZATION, HYDRODENITROGENATION, HYDROFINISHING, OR AMINE PRODUCTION H R D CORPORATION (US) 2010-08-12 WO disclosed
EP-1434758-B1 AMINONITRILE PRODUCTION INVISTA TECH SARL (US) 2007-08-22 EP disclosed
US-4003933-A Hydrogenation of nitriles in absence of secondary reaction suppressant PHILLIPS PETROLEUM COMPANY (US) 1977-01-18 US disclosed
US-4001294-A INHIBITION OF 5-METHYL-4-HEXENENITRILE FORMATION WITH ALKAKI METAL SALT OF (ALKYLENEDINITRILO)TETRA-CARBOXYLIC ACID PHILLIPS PETROLEUM COMPANY (US) 1977-01-04 US disclosed
US-3985786-A REACTING AN OLEFINICALLY UNSATURATED NITRILE, AN OLEFINIC HYDROCARBON AND THEIR MONOADDUCT IN WATER PHILLIPS PETROLEUM COMPANY (US) 1976-10-12 US disclosed
US-3980621-A Polyamides of terephthalic acid and 5-methyl-1,9-nonanediamine and fibers thereof PHILLIPS PETROLEUM COMPANY (US) 1976-09-14 US disclosed
US-3962337-A Hydrogenation of unsaturated dinitriles for employing palladium and ruthenium catalyst in aqueous tertiary alkanol PHILLIPS PETROLEUM COMPANY (US) 1976-06-08 US disclosed