Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 15/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.60 |
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | BTK | Q06187 | 2/20 | 0.54 |
| ▸ | PLK4 | O00444 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.52 |
| ▸ | CLK2 | P49760 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029110 | 0.85 | BTK (0.57) | CDC7CCNA2CDK2CCNA1DHODH | |
| SCHEMBL29709435 | 0.85 | BTK (0.57) | CDC7CCNA2CDK2CCNA1DHODH | |
| SCHEMBL6028044 | 0.84 | DHODH (0.61) | CDC7CCNA2CDK2CCNA1DHODH | |
| SCHEMBL6029606 | 0.84 | DHODH (0.78) | CDC7CCNA2CDK2CCNA1DHODH | |
| SCHEMBL6028389 | 0.83 | DHODH (0.59) | CDC7DHODHBTKPLK4PRKD3 | |
| SCHEMBL6028892 | 0.83 | DHODH (0.59) | CDC7DHODHBTKPLK4MAP4K4 | |
| SCHEMBL6028357 | 0.83 | DHODH (0.59) | CDC7CCNA2CDK2CCNA1DHODH | |
| SCHEMBL6029023 | 0.82 | HDAC11 (0.73) | CDC7CCNA2CDK2CCNA1DHODH | |
| SCHEMBL6028460 | 0.81 | BTK (0.54) | CDC7CCNA2CDK2CCNA1DHODH | |
| SCHEMBL6028084 | 0.80 | DHODH (0.59) | CDC7CCNA2CDK2CCNA1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087637-B2 | Substituted indoles which are PARP inhibitors | BASF AG (DE) | 2006-08-08 | — | — | US | disclosed |
| US-20040067949-A1 | Substituted indoles which are parp inhibitors | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067949-A1 | Substituted indoles which are parp inhibitors | PARP1, PARP2, PARP12 | CDC7 1138/4885CCNA2 503/4885CDK2 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.