Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.60 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030183 | 0.84 | F10 (1.00) | F10ABCB11F2ST14PTGS2 | |
| SCHEMBL6030137 | 0.79 | F10 (0.68) | F10ABCB11F2ST14PTGS2 | |
| SCHEMBL4028227 | 0.78 | F10 (0.82) | F10ABCB11F2ST14PTGS2 | |
| SCHEMBL5627216 | 0.78 | F10 (0.67) | F10ABCB11F2ST14PTGS2 | |
| SCHEMBL2233431 | 0.78 | F10 (0.67) | F10ABCB11F2ST14PTGS2 | |
| SCHEMBL78971 | 0.78 | F10 (0.67) | F10ABCB11F2ST14PTGS2 | |
| SCHEMBL3276611 | 0.78 | F10 (0.67) | F10ABCB11F2ST14PTGS2 | |
| SCHEMBL14838626 | 0.77 | F10 (0.67) | F10ABCB11F2ST14PTGS2 | |
| SCHEMBL16706293 | 0.77 | F10 (0.61) | F10ABCB11F2ST14PTGS2 | |
| SCHEMBL20802158 | 0.76 | F10 (0.83) | F10ABCB11F2ST14CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723164-A1 | BETA-AMINOACID-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005095440-A1 | BETA-AMINOACID-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-10-13 | — | — | WO | disclosed |