Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 5/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031159 | 0.78 | TBXA2R (0.44) | TBXA2RCNR2LMNAKDM4EMEN1 | |
| SCHEMBL2814739 | 0.71 | HRH1 (0.49) | TBXA2RCNR2LMNAKDM4EPOLB | |
| SCHEMBL5459638 | 0.71 | GAA (0.47) | LMNAKDM4EMEN1HPGDKMT2A | |
| SCHEMBL9518655 | 0.69 | TBXA2R (0.57) | TBXA2RKDM4EMEN1KMT2APTGDR | |
| SCHEMBL6032231 | 0.68 | PRMT5 (0.43) | TBXA2RLMNAKDM4ETDP1PTGDR | |
| SCHEMBL6032136 | 0.68 | MAPT (0.43) | TBXA2RTDP1PTGDR | |
| SCHEMBL1874308 | 0.67 | TBXA2R (0.62) | TBXA2RKDM4EMEN1KMT2APTGDR | |
| SCHEMBL8146918 | 0.67 | CHRM4 (0.63) | — | |
| SCHEMBL13142371 | 0.66 | CNR2 (0.54) | CNR2MEN1KMT2AHRH1HTR6 | |
| SCHEMBL30397995 | 0.66 | CA1 (0.45) | TBXA2RCNR2MEN1KMT2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678137-A1 | COMPOSITIONS AND METHODS FOR VIRAL INHIBITION | CHIRON CORPORATION (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005037791-A1 | COMPOSITIONS AND METHODS FOR VIRAL INHIBITION | CHIRON CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |