Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 11/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2712751 | 0.77 | MRGPRX4 (0.49) | ADORA1MRGPRX4MEP1BCA1CA2 | |
| SCHEMBL13555496 | 0.74 | MRGPRX4 (0.55) | MRGPRX4FOLH1MEP1BCA1CA2 | |
| SCHEMBL2712374 | 0.72 | PARP1 (0.47) | ADORA1MRGPRX4MEP1BCA1CA2 | |
| SCHEMBL28995748 | 0.71 | FOLH1 (0.51) | MRGPRX4FOLH1CA1CA2CA9 | |
| SCHEMBL2711241 | 0.70 | MRGPRX4 (0.54) | MRGPRX4FOLH1MEP1BCA1CA2 | |
| SCHEMBL6031976 | 0.67 | PARP1 (0.51) | ADORA1 | |
| SCHEMBL2713727 | 0.66 | MRGPRX4 (0.49) | ADORA1MRGPRX4FOLH1CA1CA2 | |
| SCHEMBL3226195 | 0.65 | NR4A2 (0.54) | NR4A2 | |
| SCHEMBL70351 | 0.65 | FOLH1 (0.70) | FOLH1MEP1BCA1CA2CA9 | |
| SCHEMBL30791058 | 0.65 | FOLH1 (0.70) | FOLH1MEP1BCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054367-A1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |