Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032467 | 0.94 | ESRRG (0.43) | SLC6A9SLC6A5HSP90AA1PTAFRMAPT | |
| SCHEMBL2473831 | 0.90 | MAPT (0.45) | SLC6A9SLC6A5HSP90AA1PTAFRMAPT | |
| SCHEMBL2471479 | 0.76 | MAPT (0.49) | HSP90AA1PTAFRMAPTTP53LMNA | |
| SCHEMBL2470655 | 0.74 | MAPT (0.49) | MAPTTP53TMEM97SIGMAR1LMNA | |
| SCHEMBL2469736 | 0.73 | MAPT (0.46) | HSP90AA1PTAFRMAPTTP53DRD2 | |
| SCHEMBL2469743 | 0.73 | MAPT (0.46) | HSP90AA1PTAFRMAPTTP53DRD2 | |
| SCHEMBL2471727 | 0.73 | TP53 (0.50) | MAPTTP53LMNA | |
| SCHEMBL1734794 | 0.72 | MAPT (0.53) | MAPTTP53TMEM97SIGMAR1LMNA | |
| SCHEMBL28694741 | 0.68 | MEN1 (0.73) | LMNA | |
| SCHEMBL2472568 | 0.67 | TP53 (0.49) | MAPTTP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656139-A1 | ARYL DICARBOXAMIDES | Applied Research Systems ARS Holding N.V. (AN) | 2006-05-17 | — | — | EP | claimed |
| WO-2005011685-A1 | ARYL DICARBOXAMIDES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-02-10 | — | — | WO | claimed |