Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813051 | 0.88 | TRPV1 (0.50) | TRPV1 | |
| SCHEMBL5801218 | 0.85 | TRPV1 (0.58) | TRPV1MAPK3 | |
| SCHEMBL6033610 | 0.83 | TRPV1 (0.60) | TRPV1MAPK3 | |
| SCHEMBL5800142 | 0.76 | TRPV1 (0.50) | TRPV1 | |
| SCHEMBL6033663 | 0.76 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL5809165 | 0.76 | TRPV1 (0.64) | TRPV1MAPK3 | |
| SCHEMBL6033069 | 0.75 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL6033575 | 0.74 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL6473551 | 0.74 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL6478367 | 0.73 | TRPV1 (0.58) | TRPV1MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685124-A1 | SUBSTITUTED NITROGEN-CONTAINING SIX-MEMBERED AMINO-HETEROCYCLES AS VANILLOID-1 RECEPTOR ANTAGONISTS FOR TREATING PAIN | MERCK SHARP & DOHME LTD. (GB) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005047279-A1 | SUBSTITUTED NITROGEN-CONTAINING SIX-MEMBERED AMINO-HETEROCYCLES AS VANILLOID-1 RECEPTOR ANTAGONISTS FOR TREATING PAIN | MERCK SHARP & DOHME LIMITED (GB) | 2005-05-26 | — | — | WO | disclosed |