Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | TDP2 | O95551 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033559 | 1.00 | MALT1 (0.53) | MALT1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL3797546 | 0.92 | MALT1 (0.51) | MALT1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL13123207 | 0.89 | MALT1 (0.47) | MALT1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL13123195 | 0.86 | MALT1 (0.47) | MALT1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL18774056 | 0.83 | MALT1 (0.65) | MALT1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL12473069 | 0.83 | MALT1 (0.65) | MALT1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL12473212 | 0.83 | MALT1 (0.68) | MALT1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL3797398 | 0.82 | MALT1 (0.41) | MALT1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL18774148 | 0.82 | MALT1 (0.55) | MALT1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL12473165 | 0.81 | MALT1 (0.61) | MALT1ALDH1A1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006020722-A2 | POLYMER CONJUGATES OF BETA-LAPACHONE AND BETA-LAPACHONE ANALOGS FOR TUMOR TARGETING | ARQULE, INC. (US) | 2006-02-23 | — | — | WO | disclosed |