Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 7/20 | 0.54 |
| ▸ | MAOA | P21397 | 5/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylbenzene SCHEMBL1312847 | 0.86 | TP53 (0.88) | TP53MAOATAAR1SLC6A2SMN1; SMN2 | |
| Ethylbenzene SCHEMBL9618498 | 0.86 | TP53 (0.88) | TP53MAOATAAR1SLC6A2SMN1; SMN2 | |
| Ethylbenzene SCHEMBL1331299 | 0.86 | — | — | |
| Ethylbenzene SCHEMBL11223212 | 0.86 | TP53 (1.00) | TP53TSHRTAAR1MAPTRAB9A | |
| Ethylbenzene SCHEMBL27454352 | 0.86 | TP53 (1.00) | TP53TSHRTAAR1MAPTRAB9A | |
| Ethylbenzene SCHEMBL1332452 | 0.86 | — | — | |
| Ethylbenzene SCHEMBL3987542 | 0.86 | TP53 (1.00) | TP53TSHRTAAR1MAPTRAB9A | |
| Ethylbenzene SCHEMBL1330604 | 0.86 | — | — | |
| Ethylbenzene SCHEMBL7458207 | 0.86 | TP53 (1.00) | TP53TSHRTAAR1MAPTRAB9A | |
| Ethylbenzene SCHEMBL27395806 | 0.86 | TP53 (1.00) | TP53TSHRTAAR1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1632470-A2 | Calcium receptor active molecules | NPS PHARMACEUTICALS, INC. (US) | 2006-03-08 | — | — | EP | disclosed |
| EP-1281702-B1 | Calcium receptor active molecules | NPS PHARMA INC (US) | 2005-12-21 | — | — | EP | disclosed |
| EP-1296142-B1 | Screening method for calcium receptor active molecules | NPS PHARMA INC (US) | 2005-12-07 | — | — | EP | disclosed |
| EP-1296142-A2 | Calcium receptor active molecules | NPS PHARMACEUTICALS, INC. (US) | 2003-03-26 | — | — | EP | disclosed |
| EP-1281702-A2 | Calcium receptor active molecules | NPS PHARMACEUTICALS, INC. (US) | 2003-02-05 | — | — | EP | disclosed |
| EP-0657029-A4 | CALCIUM RECEPTOR ACTIVE MOLECULES. | NPS PHARMA INC (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0657029-A1 | CALCIUM RECEPTOR ACTIVE MOLECULES | NPS PHARMACEUTICALS, INC. (US) | 1995-06-14 | — | — | EP | disclosed |
| WO-1993004373-A1 | CALCIUM RECEPTOR ACTIVE MOLECULES | NPS PHARMACEUTICALS, INC. (US) | 1993-03-04 | — | — | WO | disclosed |