Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 18/20 | 0.48 |
| ▸ | KDR | P35968 | 17/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CDK7 | P50613 | 3/20 | 0.38 |
| ▸ | CDK9 | P50750 | 3/20 | 0.38 |
| ▸ | CCNH | P51946 | 3/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034790 | 0.83 | CDK1 (0.49) | CDK1KDRCCNT1CCNB1CCNA2 | |
| SCHEMBL6034729 | 0.82 | CDK1 (0.48) | CDK1KDRCCNT1CCNB1CCNA2 | |
| SCHEMBL6034733 | 0.79 | CDK1 (0.43) | CDK1KDRCCNT1CCNB1CCNA2 | |
| SCHEMBL6033219 | 0.75 | KDR (0.67) | CDK1KDRCCNT1CCNA2CDK2 | |
| SCHEMBL6034239 | 0.74 | CDK1 (0.52) | CDK1KDRCCNT1CCNA2CDK2 | |
| SCHEMBL7514872 | 0.71 | CDK1 (0.49) | CDK1KDRCCNT1CCNA2CDK2 | |
| SCHEMBL6033236 | 0.69 | KDR (0.67) | CDK1KDRCCNT1CCNA2CDK2 | |
| SCHEMBL6033867 | 0.69 | KDR (0.48) | CDK1KDRCCNT1CCNA2CDK2 | |
| SCHEMBL6033242 | 0.68 | CDK1 (0.64) | CDK1KDRCCNT1CCNB1CCNA2 | |
| SCHEMBL6034216 | 0.67 | KDR (0.58) | CDK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187816-B1 | 5-CYANO-2-AMINOPYRIMIDINE DERIVATIVES | CELLTECH R&D LTD (GB) | 2006-12-20 | — | — | EP | disclosed |