Oxadiazoline

Oxadiazoline

SCHEMBL603568

C1=NNCO1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1013143 0.56
SCHEMBL434859 0.53
SCHEMBL3083556 0.52
SCHEMBL14693137 0.52
SCHEMBL472115 0.45
SCHEMBL6998282 0.43
SCHEMBL1652731 0.39
SCHEMBL1190870 0.39
SCHEMBL43255 0.39
SCHEMBL25230433 0.36

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 562 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085067-A1 CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF BOUNDLESS BIO INC (US) 2026-03-26 US claimed
EP-4587437-A1 CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF Boundless Bio, Inc. (US) 2025-07-23 EP claimed
US-20240425490-A1 SULFAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF BOUNDLESS BIO, INC. 2024-12-26 US claimed
CN-118488945-A Sulfonamide ribonucleotide reductase (RNR) inhibitors and uses thereof 无界生物公司 2024-08-13 CN claimed
CN-118434417-A Cyclic sulfonamide ribonucleotide reductase (RNR) inhibitors and uses thereof 无界生物公司 2024-08-02 CN claimed
EP-4402134-A1 SULFAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF Boundless Bio, Inc. (US) 2024-07-24 EP claimed
EP-4401728-A1 CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF Boundless Bio, Inc. (US) 2024-07-24 EP claimed
WO-2024059563-A1 CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF BOUNDLESS BIO, INC. (US) 2024-03-21 WO claimed
EP-3655394-B1 NOVEL ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS UNIV BERLIN TECH (DE) 2023-11-22 EP claimed
CN-116606205-A Synthetic method of ester compound 浙江工业大学 2023-08-18 CN claimed
WO-2003048081-A2 GLYCINAMIDES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-06-12 WO claimed
US-20030073836-A1 Heteroarylcarboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-04-17 US claimed
WO-2003004020-A1 HETEROARYL CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND THE USE OF THE SAME AS INHIBITORS OF THE MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN (MTP) BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2003-01-16 WO claimed
EP-1234821-A1 1,3,4-OXADIAZOLINE DERIVATIVES AND DRUGS CONTAINING THESE DERIVATIVES AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2002-08-28 EP claimed
US-5204214-A Negative images with high contrast, sensitivity, dot image quality FUJI PHOTO FILM CO., LTD. (JP) 1993-04-20 US claimed
EP-0393711-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-10-24 EP claimed
US-4914002-A High contrast image, high sensitivity FUJI PHOTO FILM CO., LTD. (JP) 1990-04-03 US claimed
US-4720451-A Silver halide color reversal light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1988-01-19 US claimed
US-4272606-A HYDRAZIDE, THIOAMIDE FUJI PHOTO FILM CO., LTD. (JP) 1981-06-09 US claimed
EP-0020304-A1 Guanidines, process for their preparation, pharmaceutical preparations containing such compounds and their application CIBA-GEIGY AG (CH) 1980-12-10 EP claimed