SCHEMBL6035950

SCHEMBL6035950

CCCCNC(=O)[C@H](N)CC(C)C

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.61
RRM1 P23921 1/20 0.56
GNAI3 P08754 1/20 0.53
GNAO1 P09471 1/20 0.53
GNAI1 P63096 1/20 0.53
MMP8 P22894 1/20 0.53
EPHX1 P07099 6/20 0.51
S1PR2 O95136 2/20 0.49
S1PR1 P21453 2/20 0.49
S1PR3 Q99500 2/20 0.49
S1PR5 Q9H228 1/20 0.49
ANPEP P15144 3/20 0.46
RNPEP Q9H4A4 2/20 0.46
DNPEP Q9ULA0 2/20 0.46
SLC7A5 Q01650 1/20 0.45
REN P00797 1/20 0.45
NOD1 Q9Y239 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3509475 1.00 DPP7 (0.61) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL11764942 1.00 DPP7 (0.61) DPP7RRM1GNAI3GNAO1GNAI1
Acetic Acid SCHEMBL11141345 0.95 DPP7 (0.56) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL10454098 0.93 DPP7 (0.67) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL20542976 0.93 DPP7 (0.67) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL3164625 0.93 DPP7 (0.67) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL20542733 0.93 DPP7 (0.67) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL20542731 0.93 DPP7 (0.67) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL30865456 0.93 DPP7 (0.67) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL3793359 0.93 DPP7 (0.67) DPP7RRM1GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060193847-A1 Peptides for inhibiting retroviruses HOWARD MARK E 2006-08-31 US disclosed
US-20030091586-A1 Peptides for inhibiting retroviruses HOWARD MARK E (US) 2003-05-15 US disclosed
EP-0971726-A4 PEPTIDES FOR INHIBITING RETROVIRUSES HOWARD MARK E (US) 2002-07-24 EP disclosed
EP-0971726-A1 PEPTIDES FOR INHIBITING RETROVIRUSES Howard, Mark E. (US) 2000-01-19 EP disclosed
WO-1998017301-A1 PEPTIDES FOR INHIBITING RETROVIRUSES HOWARD MARK E (US) 1998-04-30 WO disclosed