SCHEMBL6036855

SCHEMBL6036855

CC(=O)N(C(Cc1ccc(O)cc1)C(=O)O)P(=O)(O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.49
ESR1 P03372 3/20 0.43
ESR2 Q92731 3/20 0.43
ANPEP P15144 2/20 0.39
ERAP2 Q6P179 2/20 0.39
ERAP1 Q9NZ08 2/20 0.39
MME P08473 1/20 0.39
ACE P12821 1/20 0.39
LAP3 P28838 1/20 0.39
ENPEP Q07075 1/20 0.39
FOLH1 Q04609 1/20 0.39
TAAR1 Q96RJ0 3/20 0.38
PTPRC P08575 1/20 0.38
SLC6A2 P23975 1/20 0.38
CTSL P07711 1/20 0.37
POLB P06746 1/20 0.37
PTPN1 P18031 1/20 0.37
CPA1 P15085 1/20 0.36
CPA2 P48052 1/20 0.36
CPA4 Q9UI42 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9997409 0.81 SLC7A5 (0.50) SLC7A5ESR1ESR2ANPEPERAP2
SCHEMBL7025165 0.81 SLC7A5 (0.50) SLC7A5ESR1ESR2ANPEPERAP2
SCHEMBL7163413 0.81 SLC7A5 (0.58) SLC7A5ESR1ESR2MMEACE
SCHEMBL7163410 0.81 SLC7A5 (0.58) SLC7A5ESR1ESR2MMEACE
SCHEMBL15453746 0.79 SLC7A5 (0.45) SLC7A5ESR1ESR2ANPEPERAP2
SCHEMBL15453748 0.79 SLC7A5 (0.45) SLC7A5ESR1ESR2ANPEPERAP2
SCHEMBL8933363 0.79 SLC7A5 (0.47) SLC7A5ESR1ESR2ANPEPERAP2
SCHEMBL8933122 0.79 SLC7A5 (0.47) SLC7A5ESR1ESR2ANPEPERAP2
SCHEMBL2522740 0.78 SLC7A5 (0.54) SLC7A5ESR1ESR2MMEACE
SCHEMBL31127604 0.78 SLC7A5 (0.54) SLC7A5ESR1ESR2MMEACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1185869-B1 LIGAND-ANCHOR CONJUGATES FOR PRODUCING A BIOSENSOR LAYER GRAFFINITY PHARMACEUTICALS AG (DE) 2006-07-26 EP disclosed
US-20050153357-A1 Bioactive sensors EICHLER JUTTA (DE) 2005-07-14 US disclosed
US-20020127577-A1 Bioactive sensors GRAFFINITY PHARMACEUTICALS AG (DE) 2002-09-12 US disclosed
EP-1185869-A2 LIGAND-ANCHOR CONJUGATES FOR PRODUCING A BIOSENSOR LAYER Graffinity Pharmaceutical Design GmbH (DE) 2002-03-13 EP disclosed
WO-2000073796-A2 LIGAND-ANCHOR CONJUGATES FOR PRODUCING A BIOSENSOR LAYER GRAFFINITY PHARMACEUTICAL DESIGN GMBH (DE) 2000-12-07 WO disclosed