Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527995 | 0.84 | NOTUM (0.62) | NOTUMHSD17B3MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL12084831 | 0.77 | NOTUM (0.58) | NOTUMHSD17B3ALDH1A1ANPEP | |
| SCHEMBL20242381 | 0.76 | NOTUM (0.55) | NOTUMHSD17B3SMN1; SMN2 | |
| SCHEMBL17446878 | 0.75 | NOTUM (0.62) | NOTUMHSD17B3 | |
| SCHEMBL19411736 | 0.74 | PIK3CD (0.49) | NOTUMHSD17B3MAPTLMNAKMT2A | |
| SCHEMBL17436116 | 0.74 | NOTUM (0.63) | NOTUMHSD17B3LMNA | |
| SCHEMBL28732262 | 0.73 | NOTUM (0.39) | NOTUMHSD17B3MAPTLMNAKMT2A | |
| SCHEMBL28731112 | 0.73 | NOTUM (0.39) | NOTUMHSD17B3MAPTLMNAKMT2A | |
| SCHEMBL28924312 | 0.72 | NOTUM (0.39) | NOTUMHSD17B3KMT2ASMN1; SMN2PKM | |
| SCHEMBL17436040 | 0.72 | NOTUM (0.65) | NOTUMHSD17B3KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094031-A1 | Alpha-L-arabinofuranosidase histochemical reporter gene assay | STOWERS INSTITUTE FOR MEDICAL RESEARCH | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094031-A1 | Alpha-L-arabinofuranosidase histochemical reporter gene assay | GUSB, FUCA1, ENGASE | NOTUM 291/4885HSD17B3 872/4885MAPT 4270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.