SCHEMBL6037243

SCHEMBL6037243

OC[C@@H]1O[C@@H](Oc2c[nH]c3cc(Cl)cc(Cl)c23)[C@H](O)[C@H]1O

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 1/20 0.58
▸ SLC5A2 P31639 14/20 0.54
▸ SLC5A1 P13866 9/20 0.47
▸ SLC28A3 Q9HAS3 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9238330 0.87 ATM (0.58) ATMSLC5A2SLC5A1
SCHEMBL6037241 0.87 ATM (0.43) ATMSLC5A2SLC5A1
SCHEMBL3724838 0.85 ATM (0.65) ATMSLC5A2SLC5A1
SCHEMBL31741260 0.84 ATM (0.67) ATMSLC5A2SLC5A1
SCHEMBL3406202 0.84 ATM (0.67) ATMSLC5A2SLC5A1
SCHEMBL3719106 0.84 ATM (0.67) ATMSLC5A2SLC5A1
SCHEMBL7191502 0.84 ATM (0.67) ATMSLC5A2SLC5A1
SCHEMBL2191348 0.84 ATM (0.67) ATMSLC5A2SLC5A1
SCHEMBL3805865 0.84 ATM (0.67) ATMSLC5A2SLC5A1
SCHEMBL6037248 0.81 ATM (0.52) ATMSLC5A2SLC5A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060094031-A1 Alpha-L-arabinofuranosidase histochemical reporter gene assay STOWERS INSTITUTE FOR MEDICAL RESEARCH 2006-05-04 — — US claimed
US-20060094031-A1 Alpha-L-arabinofuranosidase histochemical reporter gene assay STOWERS INSTITUTE FOR MEDICAL RESEARCH 2006-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094031-A1 Alpha-L-arabinofuranosidase histochemical reporter gene assay GUSB, FUCA1, ENGASE ATM 4743/4885SLC5A2 780/4885SLC5A1 658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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