Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 6/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | SELP | P16109 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302816 | 0.97 | HMGCR (0.56) | HMGCRPTPN7TSHRSELPLMNA | |
| SCHEMBL11372624 | 0.93 | HMGCR (0.54) | HMGCRPTPN7TSHRSELPLMNA | |
| SCHEMBL31404952 | 0.88 | HMGCR (0.50) | HMGCRPTPN7TSHRSELPLMNA | |
| SCHEMBL9616121 | 0.88 | HMGCR (0.61) | HMGCRPTPN7TSHRSELPTHRB | |
| SCHEMBL4009864 | 0.88 | HMGCR (0.61) | HMGCRPTPN7TSHRSELPTHRB | |
| SCHEMBL9478127 | 0.88 | HMGCR (0.61) | HMGCRPTPN7TSHRSELPTHRB | |
| SCHEMBL17965814 | 0.88 | HMGCR (0.61) | HMGCRPTPN7TSHRSELPTHRB | |
| SCHEMBL4595942 | 0.87 | HMGCR (0.60) | HMGCRPTPN7TSHRSELPTHRB | |
| SCHEMBL15766347 | 0.87 | HMGCR (0.50) | HMGCRPTPN7TSHRSELPKDM4E | |
| SCHEMBL19148481 | 0.87 | HMGCR (0.50) | HMGCRPTPN7TSHRSELPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223947-A1 | Chemical synthesis of polymeric nanomaterials and carbon nanomaterials | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-10-05 | — | — | US | claimed |
| US-20060223947-A1 | Chemical synthesis of polymeric nanomaterials and carbon nanomaterials | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-10-05 | — | — | US | disclosed |