Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18191271 | 0.85 | TSHR (0.58) | TSHRPTPN7GLAALDH1A1LMNA | |
| SCHEMBL18191267 | 0.81 | TSHR (0.41) | TSHRPTPN7GLAALDH1A1LMNA | |
| SCHEMBL16201810 | 0.81 | TSHR (0.48) | TSHRPTPN7ALDH1A1LMNAHMGCR | |
| SCHEMBL18263707 | 0.76 | PTPN7 (0.64) | TSHRPTPN7ALDH1A1HMGCRPPARG | |
| SCHEMBL15284077 | 0.75 | TSHR (0.57) | TSHRPTPN7GLAALDH1A1LMNA | |
| SCHEMBL940491 | 0.74 | HMGCR (0.66) | TSHRPTPN7HMGCRSELP | |
| SCHEMBL9607107 | 0.74 | TSHR (0.48) | TSHRPTPN7ALDH1A1LMNAHMGCR | |
| SCHEMBL21544536 | 0.74 | HMGCR (0.66) | TSHRPTPN7HMGCRSELP | |
| SCHEMBL11311701 | 0.74 | HMGCR (0.66) | TSHRPTPN7ALDH1A1LMNAHMGCR | |
| SCHEMBL940458 | 0.74 | HMGCR (0.66) | TSHRPTPN7HMGCRSELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223947-A1 | Chemical synthesis of polymeric nanomaterials and carbon nanomaterials | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-10-05 | — | — | US | disclosed |