⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22269 | 1.00 | — | — | |
| SCHEMBL2184624 | 1.00 | — | — | |
| SCHEMBL1355142 | 1.00 | — | — | |
| SCHEMBL19521748 | 1.00 | — | — | |
| SCHEMBL22270 | 1.00 | — | — | |
| SCHEMBL1355800 | 1.00 | — | — | |
| SCHEMBL31416087 | 1.00 | — | — | |
| SCHEMBL2184981 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL25230162 | 0.98 | CYP2D6 (0.56) | — | |
| Hydrochloric Acid SCHEMBL26120219 | 0.98 | CYP2D6 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-9422566-B2 | Gene cluster for biosynthesis of griselimycin and methylgriselimycin | SANOFI (FR) | 2016-08-23 | — | — | US | disclosed |
| US-20140295457-A1 | GENE CLUSTER FOR BIOSYNTHESIS OF GRISELIMYCIN AND METHYLGRISELIMYCIN | SANOFI (FR) | 2014-10-02 | — | — | US | disclosed |
| US-20060183888-A1 | Pyrrolysine synthesis and modification | NIH - DEITR | 2006-08-17 | — | — | US | disclosed |
| US-20060166319-A1 | Charging tRNA with pyrrolysine | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-07-27 | — | — | US | disclosed |