Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 9/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11584047 | 1.00 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1HTTALOX15GLO1 | |
| SCHEMBL27751330 | 0.98 | HTT (0.53) | HSP90AA1HSP90AB1HTTALOX15GLO1 | |
| SCHEMBL11149010 | 0.94 | HTT (0.54) | HSP90AA1HSP90AB1HTTALOX15GLO1 | |
| SCHEMBL15923243 | 0.92 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1HTTALOX15GLO1 | |
| Quinoline SCHEMBL28154730 | 0.90 | TLR8 (0.48) | HSP90AA1HSP90AB1HTTALOX15GLO1 | |
| SCHEMBL9180960 | 0.87 | HTT (0.57) | HSP90AA1HSP90AB1HTTALOX15GLO1 | |
| SCHEMBL1507837 | 0.87 | MEN1 (0.56) | HSP90AA1HSP90AB1HTTALOX15GLO1 | |
| SCHEMBL522650 | 0.84 | MEN1 (0.59) | HSP90AA1HSP90AB1HTTALOX15GLO1 | |
| SCHEMBL26079033 | 0.83 | HDAC6 (0.60) | HSP90AA1HSP90AB1HTTALOX15GLO1 | |
| SCHEMBL6222568 | 0.80 | KMT2A (0.56) | HSP90AA1HTTALOX15GLO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
| US-4113717-A | Quaternized azo dyestuffs | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | HSP90AA1 2381/4885HSP90AB1 2055/4885HTT 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.