Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 9/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.37 |
| ▸ | BID | P55957 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038014 | 1.00 | HDAC2 (0.45) | HDAC2HDAC8HDAC6HRH3RAB9A | |
| SCHEMBL6037986 | 0.85 | HDAC2 (0.50) | HDAC2HDAC8HDAC6HRH3RAB9A | |
| SCHEMBL6037990 | 0.85 | HDAC2 (0.50) | HDAC2HDAC8HDAC6HRH3RAB9A | |
| SCHEMBL5283316 | 0.77 | HDAC2 (0.59) | HDAC2HDAC8HDAC6 | |
| SCHEMBL5283302 | 0.77 | HDAC2 (0.59) | HDAC2HDAC8HDAC6 | |
| SCHEMBL5081643 | 0.77 | HDAC6 (0.72) | HDAC2HDAC8HDAC6RAB9A | |
| SCHEMBL5078378 | 0.77 | HDAC6 (0.72) | HDAC2HDAC8HDAC6RAB9A | |
| SCHEMBL5078374 | 0.77 | HDAC6 (0.72) | HDAC2HDAC8HDAC6RAB9A | |
| SCHEMBL5282091 | 0.76 | HDAC2 (0.56) | HDAC2HDAC8HDAC6MAPT | |
| SCHEMBL5278026 | 0.72 | HDAC2 (0.62) | HDAC2HDAC8HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | claimed |
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | HDAC2 5/4885HDAC8 11/4885HDAC6 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.