SCHEMBL6038680

SCHEMBL6038680

Cc1ccc(S(=O)(=O)Nc2nccnc2OCc2cccc(OC(C)C)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.46
AR P10275 1/20 0.45
FFAR4 Q5NUL3 1/20 0.43
PPIF P30405 1/20 0.43
ALDH1A1 P00352 4/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 1/20 0.42
MEN1 O00255 1/20 0.42
CCR4 P51679 1/20 0.41
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
POLB P06746 1/20 0.39
CYP19A1 P11511 2/20 0.39
KAT6A Q92794 1/20 0.39
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6038407 0.89 F2 (0.45) F2ARPPIFALDH1A1KMT2A
SCHEMBL6038504 0.89 MEN1 (0.50) F2ARPPIFALDH1A1KMT2A
SCHEMBL6038899 0.88 F2 (0.47) F2ARPPIFALDH1A1KMT2A
SCHEMBL6039298 0.87 AR (0.51) F2ARPPIFALDH1A1KMT2A
SCHEMBL6038725 0.86 KMT2A (0.48) F2ARPPIFALDH1A1KMT2A
SCHEMBL6038316 0.86 F2 (0.46) F2ARPPIFALDH1A1KMT2A
SCHEMBL6038839 0.85 F2 (0.49) F2ARPPIFALDH1A1KMT2A
SCHEMBL6038428 0.84 F2 (0.48) F2ARPPIFALDH1A1KMT2A
SCHEMBL6038703 0.83 KMT2A (0.54) F2ARPPIFALDH1A1KMT2A
SCHEMBL6039011 0.83 KMT2A (0.47) ARPPIFALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060004010-A1 Ccr4 antagonist and medical use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2006-01-05 US disclosed
EP-1541563-A1 CCR4 ANTAGONIST AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2005-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060004010-A1 Ccr4 antagonist and medical use thereof CCR4, CCR1, CCR9 F2 2305/4885AR 422/4885FFAR4 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.