Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 14/20 | 0.53 |
| ▸ | EDNRA | P25101 | 6/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038857 | 0.90 | CCR4 (0.52) | CCR4EDNRA | |
| SCHEMBL6038770 | 0.86 | CCR4 (0.56) | CCR4EDNRACCR5 | |
| SCHEMBL6038742 | 0.86 | CCR4 (0.71) | CCR4EDNRA | |
| SCHEMBL6038713 | 0.85 | CCR4 (0.61) | CCR4EDNRA | |
| SCHEMBL6038658 | 0.85 | CCR4 (0.70) | CCR4EDNRACCR5 | |
| SCHEMBL6038696 | 0.85 | EDNRA (0.54) | CCR4EDNRA | |
| SCHEMBL6038568 | 0.84 | CCR4 (0.58) | CCR4EDNRACCR5 | |
| SCHEMBL6038628 | 0.84 | CCR4 (0.53) | CCR4EDNRA | |
| SCHEMBL6038825 | 0.84 | CCR4 (0.53) | CCR4EDNRA | |
| SCHEMBL6038961 | 0.83 | EDNRA (0.56) | CCR4EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004010-A1 | Ccr4 antagonist and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-05 | — | — | US | disclosed |
| EP-1541563-A1 | CCR4 ANTAGONIST AND MEDICINAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004010-A1 | Ccr4 antagonist and medical use thereof | CCR4, CCR1, CCR9 | CCR4 1/4885EDNRA 512/4885CCR5 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.