Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | APLNR | P35414 | 1/20 | 0.57 |
| ▸ | GLP1R | P43220 | 1/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.57 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2862202 | 0.99 | NPSR1 (0.63) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| SCHEMBL2865266 | 0.91 | NPSR1 (0.69) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| Hydrochloric Acid SCHEMBL2863720 | 0.87 | NPSR1 (0.61) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| SCHEMBL2858322 | 0.83 | NPSR1 (0.54) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| SCHEMBL2859470 | 0.81 | NPSR1 (0.54) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| SCHEMBL5582137 | 0.81 | NPSR1 (0.52) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| SCHEMBL2863356 | 0.81 | NPSR1 (0.55) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| Hydrochloric Acid SCHEMBL2862197 | 0.80 | NPSR1 (0.61) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| SCHEMBL2865324 | 0.78 | NPSR1 (1.00) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| SCHEMBL2861754 | 0.78 | NPSR1 (0.82) | NPSR1ADRB2APLNRGLP1RFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661898-A1 | BICYCLIC PIPERAZINE COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2006-05-31 | — | — | EP | disclosed |