SCHEMBL6040446

SCHEMBL6040446

NC(=S)C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiourea SCHEMBL31380303 0.67
SCHEMBL10526600 0.67
SCHEMBL30169 0.64
SCHEMBL13087605 0.64
SCHEMBL442109 0.64
SCHEMBL10676515 0.64
SCHEMBL44759 0.64
SCHEMBL5747213 0.64
SCHEMBL11120443 0.64
Thiourea SCHEMBL850383 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1138765-C Oxazolidinone antibacterial agents with thiocarbonyl functionality �������Ŷ���Լ��������˾ 2004-02-18 CN claimed
CN-1257486-A Oxazolidinone antibacterial agents with thiocarbonyl functionality UPJOHN CO (US) 2000-06-21 CN claimed
US-7049443-B2 Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound PHARMACIA & UPJOHN COMPANY (US) 2006-05-23 US disclosed
EP-1451164-A2 AMIDE DERIVATIVES HAVING IMPROVED SOLUBILITY PHARMACIA &amp; UPJOHN COMPANY (US) 2004-09-01 EP disclosed
CN-1138765-C Oxazolidinone antibacterial agents with thiocarbonyl functionality �������Ŷ���Լ��������˾ 2004-02-18 CN disclosed
WO-2003006440-A2 AMIDE-CONTAINING COMPOUND HAVING IMPROVED SOLUBILITY AND METHOD OF IMPROVING THE SOLUBILITY OF AN AMIDE-CONTAINING COMPOUND PHARMACIA & UPJOHN COMPANY (US) 2003-01-23 WO disclosed
CN-1322204-A Oxazolidinone antibacterial agents having thiocarbonyl functionality PHARMACIA & VPJOHN CO (US) 2001-11-14 CN disclosed
CN-1257486-A Oxazolidinone antibacterial agents with thiocarbonyl functionality UPJOHN CO (US) 2000-06-21 CN disclosed