Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 17/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6040461 | 1.00 | TNFRSF1A (0.55) | TNFRSF1AERN1ABCB1 | |
| SCHEMBL6040786 | 0.85 | TNFRSF1A (0.62) | TNFRSF1AERN1 | |
| SCHEMBL6040783 | 0.85 | TNFRSF1A (0.62) | TNFRSF1AERN1 | |
| SCHEMBL6040716 | 0.80 | TNFRSF1A (0.72) | TNFRSF1A | |
| SCHEMBL6040718 | 0.80 | TNFRSF1A (0.72) | TNFRSF1A | |
| SCHEMBL6040703 | 0.80 | TNFRSF1A (0.55) | TNFRSF1A | |
| SCHEMBL6040698 | 0.80 | TNFRSF1A (0.55) | TNFRSF1A | |
| SCHEMBL30382753 | 0.80 | TNFRSF1A (0.55) | TNFRSF1A | |
| SCHEMBL25219708 | 0.76 | TNFRSF1A (0.49) | TNFRSF1A | |
| SCHEMBL31233349 | 0.76 | TNFRSF1A (0.49) | TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094801-B2 | Chalcone derivatives and their use to treat diseases | ATHEROGENICS, INC. (US) | 2006-08-22 | — | — | US | claimed |