Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.67 |
| ▸ | MAOB | P27338 | 7/20 | 0.60 |
| ▸ | MAOA | P21397 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | CALML3 | P27482 | 1/20 | 0.57 |
| ▸ | SDHA | P31040 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160666 | 1.00 | F10 (0.67) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL7158513 | 0.98 | F10 (0.67) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL7158515 | 0.98 | F10 (0.67) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL7154244 | 0.97 | F10 (0.66) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL7154240 | 0.97 | F10 (0.66) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL6040212 | 0.97 | F10 (0.71) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL6157400 | 0.97 | F10 (0.71) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL7710384 | 0.92 | F10 (0.57) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL7710379 | 0.92 | F10 (0.57) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL7707253 | 0.91 | MAOB (0.67) | F10MAOBMAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362189-B1 | GRAMNEGATIVE, GRAMPOSITIVE BACTERIA | PHARMACIA AND UPJOHN COMPANY | 2002-03-26 | — | — | US | claimed |
| US-7049443-B2 | Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound | PHARMACIA & UPJOHN COMPANY (US) | 2006-05-23 | — | — | US | disclosed |
| US-6537986-B2 | With thiourea, thioamide, or dithiocarbamate functionality; (S)-N-(((3-(3-fluoro-4-morpholinyl)phenyl)-2-oxo-5 -oxazolidinyl)methyl)thioacetamide for example; treats multiple-resistant staphylococci | PHARMACIA & UPJOHN COMPANY | 2003-03-25 | — | — | US | disclosed |
| US-6362189-B1 | GRAMNEGATIVE, GRAMPOSITIVE BACTERIA | PHARMACIA AND UPJOHN COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6342513-B1 | THIOCARBONYLAMIDES ON OXAZO-, ISOOXAZOLE OR FURANONE RINGS FOR USE AS BACTERICIDES | PHARMACIA AND UPJOHN COMPANY | 2002-01-29 | — | — | US | disclosed |
| US-6255304-B1 | AIDS THERAPY | PHARMACIA & UPJOHN COMPANY | 2001-07-03 | — | — | US | disclosed |