Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8513374 | 0.97 | TSHR (0.37) | TSHRMAPK1MEN1KMT2A | |
| SCHEMBL10780920 | 0.95 | TSHR (0.32) | TSHRMAPK1MEN1KMT2A | |
| SCHEMBL9732148 | 0.92 | TSHR (0.33) | TSHRMAPK1MEN1KMT2A | |
| SCHEMBL10774463 | 0.87 | TSHR (0.30) | TSHRMAPK1 | |
| SCHEMBL28234695 | 0.81 | MEN1 (0.55) | TSHRMAPK1MEN1KMT2A | |
| SCHEMBL2745616 | 0.81 | TSHR (0.36) | TSHR | |
| SCHEMBL26967107 | 0.80 | — | — | |
| Butane SCHEMBL28490969 | 0.79 | TSHR (0.46) | TSHRMEN1KMT2A | |
| SCHEMBL28474594 | 0.78 | — | — | |
| SCHEMBL10617522 | 0.78 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4594238-A | Administering platinum compound; then platimun binding compound | REGENTS OF UNIVERSITY OF MINNESOTA (US) | 1986-06-10 | — | — | US | claimed |
| US-7071158-B2 | Antioxidant enhancement of therapy for hyperproliferative conditions | ATHEROGENICS, INC. (US) | 2006-07-04 | — | — | US | disclosed |
| US-20010049349-A1 | Antioxidant enhancement of therapy for hyperproliferative conditions | CRABTREE ACQUISITION CO, LLC | 2001-12-06 | — | — | US | disclosed |
| EP-0433393-B1 | TREATMENT OF DAMAGED BONE MARROW AND DOSAGE UNITS THEREFOR | UNIV ROCHESTER (US) | 1995-03-15 | — | — | EP | disclosed |
| US-5187193-A | Administering dithiocarbamate derivative | UNIVERSITY OF ROCHESTER (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0433393-A4 | TREATMENT OF DAMAGED BONE MARROW AND DOSAGE UNITS THEREFOR | — | 1992-01-15 | — | — | EP | disclosed |
| US-5035878-A | Reversing bone marrow damage resulting from chemotherapy | UNIVERSITY OF ROCHESTER (US) | 1991-07-30 | — | — | US | disclosed |
| EP-0433393-A1 | TREATMENT OF DAMAGED BONE MARROW AND DOSAGE UNITS THEREFOR. | UNIV ROCHESTER (US) | 1991-06-26 | — | — | EP | disclosed |
| WO-1991005571-A1 | METHOD FOR PRODUCING BONE MARROW GROWTH CELL FACTORS | UNIVERSITY OF ROCHESTER (US) | 1991-05-02 | — | — | WO | disclosed |
| US-4938949-A | Combatting side effects of anticancer drugs with dithiocarbamates | UNIVERSITY OF NEW YORK (US) | 1990-07-03 | — | — | US | disclosed |
| WO-1990002550-A1 | TREATMENT OF DAMAGED BONE MARROW AND DOSAGE UNITS THEREFOR | UNIVERSITY OF ROCHESTER (US) | 1990-03-22 | — | — | WO | disclosed |
| US-4594238-A | Administering platinum compound; then platimun binding compound | REGENTS OF UNIVERSITY OF MINNESOTA (US) | 1986-06-10 | — | — | US | disclosed |