Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 1.00 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 1.00 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.97 |
| ▸ | FAP | Q12884 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14392566 | 1.00 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL6041038 | 1.00 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL18524455 | 0.92 | DPP4 (0.88) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL6165642 | 0.92 | DPP4 (0.86) | DPP4DPP8DPP7DPP9FAP | |
| Trifluoroacetic Acid SCHEMBL5646494 | 0.91 | DPP4 (0.82) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL6359545 | 0.88 | DPP4 (0.81) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8282165 | 0.87 | DPP4 (0.79) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL6365008 | 0.87 | DPP4 (0.79) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL6359541 | 0.86 | DPP4 (0.77) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL6359544 | 0.86 | DPP4 (0.77) | DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060024313-A1 | Agents that disrupt dimer formation in DPP-IV family of prolyl dipeptidases | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2006-02-02 | — | — | US | disclosed |