Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 0.67 |
| ▸ | ABL1 | P00519 | 7/20 | 0.56 |
| ▸ | EGFR | P00533 | 7/20 | 0.56 |
| ▸ | ABL2 | P42684 | 7/20 | 0.56 |
| ▸ | CDK1 | P06493 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | TPO | P07202 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820786 | 0.94 | SRC (0.65) | SRCABL1EGFRABL2CDK1 | |
| SCHEMBL7845672 | 0.86 | SRC (0.89) | SRCABL1EGFRABL2CDK1 | |
| SCHEMBL8820549 | 0.85 | SRC (0.53) | SRCABL1EGFRABL2CDK1 | |
| SCHEMBL8819623 | 0.83 | SRC (0.61) | SRCABL1EGFRABL2CDK1 | |
| SCHEMBL8820841 | 0.82 | SRC (0.61) | SRCABL1EGFRABL2CDK1 | |
| SCHEMBL8820820 | 0.81 | SRC (0.48) | SRCABL1EGFRABL2CDK1 | |
| SCHEMBL7847645 | 0.80 | SRC (1.00) | SRCABL1EGFRABL2CDK1 | |
| SCHEMBL8820855 | 0.79 | SRC (0.53) | SRCABL1EGFRABL2CDK1 | |
| SCHEMBL7841567 | 0.77 | SRC (0.75) | SRCABL1EGFRABL2CDK1 | |
| SCHEMBL7847554 | 0.77 | SRC (0.80) | SRCABL1EGFRABL2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060030017-A1 | Three-dimensional structure of c-Abl | FENDRICH GABRIELE | 2006-02-09 | — | — | US | disclosed |