⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928699 | 0.67 | — | — | |
| SCHEMBL780554 | 0.65 | — | — | |
| SCHEMBL29214069 | 0.65 | — | — | |
| SCHEMBL777370 | 0.62 | — | — | |
| SCHEMBL777011 | 0.62 | — | — | |
| SCHEMBL19197521 | 0.60 | — | — | |
| SCHEMBL4125788 | 0.60 | — | — | |
| SCHEMBL23901815 | 0.58 | — | — | |
| SCHEMBL16269760 | 0.58 | — | — | |
| SCHEMBL23706713 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293751-B2 | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia | ARENA PHARMACEUTICALS, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-20060217379-A1 | 1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia | ARENA PHARMACEUTICALS | 2006-09-28 | — | — | US | disclosed |
| CN-1172477-A | Substituted 2 -phenylpyridines as herbicides | BASF AG (DE) | 1998-02-04 | — | — | CN | disclosed |