Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.76 |
| ▸ | BCR | P11274 | 11/20 | 0.76 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.76 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.76 |
| ▸ | PRKCA | P17252 | 4/20 | 0.76 |
| ▸ | SRC | P12931 | 7/20 | 0.60 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.57 |
| ▸ | PRKCG | P05129 | 1/20 | 0.57 |
| ▸ | PRKCB | P05771 | 1/20 | 0.57 |
| ▸ | PRKCH | P24723 | 1/20 | 0.57 |
| ▸ | PRKCI | P41743 | 1/20 | 0.57 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.57 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.57 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.57 |
| ▸ | ABL2 | P42684 | 2/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4896152 | 0.89 | ABL1 (0.84) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL4905407 | 0.89 | ABL1 (0.74) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL9642 | 0.86 | ABL1 (1.00) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL6041113 | 0.82 | ABL1 (0.57) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL6041110 | 0.82 | ABL1 (0.57) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL4896241 | 0.80 | ABL1 (0.71) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL4903369 | 0.80 | ABL1 (0.71) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL4892512 | 0.79 | ABL1 (0.67) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL3123402 | 0.78 | ABL1 (0.74) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL4901694 | 0.77 | ABL1 (0.83) | ABL1BCRPDGFRBPDGFRAPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060217404-A1 | Pyridylpyrimidine derivatives as effective compounds against prion infections and prion diseases | GPC BIOTECH FORSCHUNGSGESELLSCHAFT MBH (DE) | 2006-09-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217404-A1 | Pyridylpyrimidine derivatives as effective compounds against prion infections and prion diseases | PRNP, PPM1D, PPM1F | ABL1 904/4885BCR 1230/4885PDGFRB 2329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.