Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL18140271 | 0.93 | TSHR (0.39) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| Adipic Acid SCHEMBL18139193 | 0.92 | TSHR (0.38) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| Adipic Acid SCHEMBL18139576 | 0.92 | TSHR (0.38) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL18140084 | 0.92 | TSHR (0.41) | TSHRALDH1A1LMNATDP1 | |
| Adipic Acid SCHEMBL18140295 | 0.92 | TSHR (0.38) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| Adipic Acid SCHEMBL18141643 | 0.92 | TSHR (0.38) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| Pimelic Acid SCHEMBL18139777 | 0.92 | TSHR (0.41) | TSHRALDH1A1LMNATDP1 | |
| Adipic Acid SCHEMBL18141404 | 0.92 | TSHR (0.38) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| Adipic Acid SCHEMBL18139810 | 0.92 | TSHR (0.38) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| Octanedioate SCHEMBL18140089 | 0.92 | TSHR (0.41) | TSHRALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962741-B2 | Thermally curable resin composition for protective film | LG CHEM, LTD. (KR) | 2015-02-24 | — | — | US | claimed |
| US-20120041120-A1 | THERMALLY CURABLE RESIN COMPOSITION FOR PROTECTIVE FILM | LG CHEM. LTD. (KR) | 2012-02-16 | — | — | US | claimed |
| US-8962741-B2 | Thermally curable resin composition for protective film | LG CHEM, LTD. (KR) | 2015-02-24 | — | — | US | disclosed |
| US-20120041120-A1 | THERMALLY CURABLE RESIN COMPOSITION FOR PROTECTIVE FILM | LG CHEM. LTD. (KR) | 2012-02-16 | — | — | US | disclosed |