Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | GBA1 | P04062 | 2/20 | 1.00 |
| ▸ | CA12 | O43570 | 6/20 | 0.75 |
| ▸ | CA9 | Q16790 | 6/20 | 0.75 |
| ▸ | POLB | P06746 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | GLA | P06280 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743424 | 0.87 | KMT2A (0.78) | KMT2AGBA1CA12CA9POLB | |
| SCHEMBL15335372 | 0.86 | KMT2A (1.00) | KMT2AGBA1CA12CA9POLB | |
| SCHEMBL6741793 | 0.85 | GBA1 (0.79) | KMT2AGBA1CA12CA9POLB | |
| SCHEMBL30186490 | 0.85 | KMT2A (0.74) | KMT2AGBA1CA12CA9POLB | |
| SCHEMBL23731512 | 0.85 | KMT2A (0.74) | KMT2AGBA1CA12CA9POLB | |
| SCHEMBL18288754 | 0.83 | KMT2A (0.70) | KMT2AGBA1CA12CA9POLB | |
| SCHEMBL9006755 | 0.83 | KMT2A (0.70) | KMT2AGBA1CA12CA9POLB | |
| SCHEMBL21194993 | 0.82 | KMT2A (0.70) | KMT2AGBA1CA12CA9POLB | |
| SCHEMBL12633719 | 0.82 | KMT2A (0.68) | KMT2AGBA1MEN1GAATDP1 | |
| SCHEMBL13384905 | 0.81 | KMT2A (0.67) | KMT2AGBA1CA12CA9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839185-B1 | SCREENING METHODS FOR ENZYMES AND ENZYME KITS | DIVERSA CORP (US) | 2006-11-22 | — | — | EP | disclosed |
| US-20020058254-A1 | Screening methods for enzymes and enzyme kits | DIVERSA CORPORATION | 2002-05-16 | — | — | US | disclosed |