⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6045389 | 0.95 | MPI (0.31) | — | |
| SCHEMBL4066409 | 0.83 | — | — | |
| SCHEMBL139867 | 0.81 | PTPN1 (0.38) | — | |
| SCHEMBL6429913 | 0.81 | PTPN1 (0.38) | — | |
| SCHEMBL10380111 | 0.79 | PTPN1 (0.32) | — | |
| SCHEMBL15127430 | 0.79 | MPI (0.33) | — | |
| SCHEMBL7104411 | 0.75 | BTN3A1 (0.39) | — | |
| SCHEMBL320909 | 0.73 | BTN3A1 (0.37) | — | |
| SCHEMBL27743391 | 0.73 | AKR1B1 (0.33) | — | |
| SCHEMBL199123 | 0.73 | AKR1B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183886-A1 | Ligands to enhance cellular uptake of biomolecules | CELL WORKS THERAPEUTICS, INC., A DELAWARE CORPORATION | 2006-08-17 | — | — | US | claimed |
| EP-1409548-A4 | LIGANDS TO ENHANCE CELLULAR UPTAKE OF BIOMOLECULES | CELL WORKS THERAPEUTICS INC (US) | 2005-08-31 | — | — | EP | claimed |
| EP-1409548-A2 | LIGANDS TO ENHANCE CELLULAR UPTAKE OF BIOMOLECULES | Cell Works Inc. (US) | 2004-04-21 | — | — | EP | claimed |
| WO-2003067209-A2 | LIGANDS TO ENHANCE CELLULAR UPTAKE OF BIOMOLECULES | CELL WORKS INC. (US) | 2003-08-14 | — | — | WO | claimed |
| US-20030119724-A1 | Ligands to enhance cellular uptake of biomolecules | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-06-26 | — | — | US | claimed |