Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985757 | 0.88 | SMN1; SMN2 (0.75) | SMN1; SMN2SIGMAR1TSHROPRM1CA12 | |
| SCHEMBL593215 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2SIGMAR1TSHROPRM1CA12 | |
| SCHEMBL7705959 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2SIGMAR1LMNAKDM4EMAPT | |
| SCHEMBL20187096 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2SIGMAR1KDM4EMAPTOPRM1 | |
| SCHEMBL654710 | 0.86 | SMN1; SMN2 (0.64) | SMN1; SMN2SIGMAR1LMNAMAPTOPRM1 | |
| SCHEMBL16876721 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2SIGMAR1MAPTTSHROPRM1 | |
| SCHEMBL20187152 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2SIGMAR1MAPTOPRM1CA12 | |
| SCHEMBL16876707 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2SIGMAR1OPRM1CA12CA1 | |
| SCHEMBL11565080 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2SIGMAR1LMNAKDM4EMAPT | |
| SCHEMBL4213929 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2SIGMAR1LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-11-09 | — | — | US | disclosed |
| EP-1559428-A1 | RECEPTOR REGULATOR | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | NMUR1, NMUR2, NMBR | SMN1; SMN2 2715/4885SIGMAR1 179/4885LMNA 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.