⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047009 | 0.75 | — | — | |
| SCHEMBL5668991 | 0.72 | TSHR (0.36) | — | |
| SCHEMBL9434905 | 0.70 | BRD4 (0.43) | — | |
| SCHEMBL11033699 | 0.69 | PIK3CD (0.42) | — | |
| SCHEMBL9634467 | 0.69 | BRD4 (0.41) | — | |
| SCHEMBL20909425 | 0.69 | BRD4 (0.41) | — | |
| SCHEMBL22635867 | 0.68 | BRD4 (0.41) | — | |
| SCHEMBL6645160 | 0.67 | BRD4 (0.40) | — | |
| SCHEMBL7029657 | 0.67 | BRD4 (0.39) | — | |
| SCHEMBL6348535 | 0.66 | BRD4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160988-A1 | Heterocycle functionalized dendritic polymers | DENDRITIC NANOTECHNOLOGIES, INC. | 2006-07-20 | — | — | US | disclosed |
| US-20050171298-A1 | Pyrrolidone, piperidone and azetidinone terminated and functionalizes dendritic polymers | DENDRITIC NANOTECHNOLOGIES, INC. | 2005-08-04 | — | — | US | disclosed |