⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28286705 | 0.71 | — | — | |
| SCHEMBL7031710 | 0.71 | — | — | |
| SCHEMBL2396970 | 0.71 | — | — | |
| SCHEMBL1536260 | 0.69 | — | — | |
| SCHEMBL2466171 | 0.69 | — | — | |
| SCHEMBL2468752 | 0.69 | — | — | |
| SCHEMBL16969682 | 0.67 | — | — | |
| SCHEMBL16969926 | 0.67 | — | — | |
| SCHEMBL6933702 | 0.67 | — | — | |
| SCHEMBL8818224 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418361-B | It is used to prepare the integral method of Z-1,1,1,4,4,4- hexafluoro -2- butylene | 得凯莫斯公司弗罗里达有限公司 | 2019-07-09 | — | — | CN | disclosed |
| EP-1558603-B1 | OXYGE-CONTAINING HETEROCYCLIC FUSED NAPHTHOPYRANS | INSIGHT EQUITY A P X LP (US) | 2015-07-22 | — | — | EP | disclosed |
| EP-2578589-A1 | Oxygen-containing heterocyclic fused naphthopyrans having photochromic properties | Insight Equity A.P.X., LP (US) | 2013-04-10 | — | — | EP | disclosed |
| US-7074943-B2 | Oxygen-containing heterocyclic fused naphthopyrans | VISION-EASE LENS (US) | 2006-07-11 | — | — | US | disclosed |
| US-7008568-B2 | Photochromic naphthopyran compounds: compositions and articles containing those naphthopyran compounds | VISION-EASE LENS, INC. (US) | 2006-03-07 | — | — | US | disclosed |
| US-20060030673-A1 | Oxygen-containing heterocyclic fused naphthopyrans | HOYA OPTICAL LABS OF AMERICA, INC. | 2006-02-09 | — | — | US | disclosed |
| US-6963003-B2 | Oxygen-containing heterocyclic fused naphthopyrans | VISION-EASE LANE (US) | 2005-11-08 | — | — | US | disclosed |
| US-6858732-B2 | Photochromic benzodioxine fused naphthopyran compounds, compositions and articles containing those naphthopyran compounds | VISION-EASE LENS, INC. (US) | 2005-02-22 | — | — | US | disclosed |
| US-20040215024-A1 | Oxygen-containing heterocyclic fused naphthopyrans | VISION-EASE LENS, INC. | 2004-10-28 | — | — | US | disclosed |
| WO-2003074528-A1 | PHOTOCHROMIC BENZODIOXINE - FUSED NAPHTHOPYRAN COMPOUNDS AND COMPOSITIONS AND ARTICLES CONTAINING THEM | VISION-EASE LENS, INC. (US) | 2003-09-12 | — | — | WO | disclosed |
| US-20030168645-A1 | Photochromic benzodioxine fused naphthopyran compounds, compositions and articles containing those naphthopyran compounds | VISION-EASE LENS, INC. | 2003-09-11 | — | — | US | disclosed |
| US-6608215-B2 | Photochromic ophthalmic or sun protection lenses, glass paneling | VISION-EASE LENS, INC. | 2003-08-19 | — | — | US | disclosed |
| US-20030146419-A1 | Photochromic naphthopyran compounds: compositions and articles containing those naphthopyran compounds | VISION-EASE LENS, INC. | 2003-08-07 | — | — | US | disclosed |
| US-20030092918-A1 | Oxygen-containing heterocyclic fused naphthopyrans | VISION-EASE LENS, INC. | 2003-05-15 | — | — | US | disclosed |
| WO-2003025638-A1 | OXYGEN-CONTAINING HETEROCYCLIC FUSED NAPHTHOPYRANS | VISION-EASE LENS, INC. (US) | 2003-03-27 | — | — | WO | disclosed |
| US-4699949-A | Hardening of acid-hardenable compositions containing a blocked hardening catalyst, using heat | CIBA-GEIGY CORPORATION (US) | 1987-10-13 | — | — | US | disclosed |
| EP-0132225-B1 | CURING OF ACID-CURABLE COMPOSITIONS CONTAINING A BLOCKED CATALYST WITH THE AID OF HEAT | CIBA-GEIGY AG (CH) | 1987-08-19 | — | — | EP | disclosed |
| EP-0132225-A2 | Curing of acid-curable compositions containing a blocked catalyst with the aid of heat | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | disclosed |