Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770399 | 0.96 | CA4 (0.46) | CA4FAHD1CA1MEN1LDHA | |
| SCHEMBL22781 | 0.96 | — | — | |
| Bicarbonate SCHEMBL4143151 | 0.93 | CA4 (0.38) | CA4FAHD1CA1MEN1LDHA | |
| Water SCHEMBL11774765 | 0.92 | — | — | |
| Bicarbonate SCHEMBL9296545 | 0.92 | CA1 (0.33) | CA4FAHD1CA1 | |
| Hydrogen Peroxide SCHEMBL4303609 | 0.92 | — | — | |
| SCHEMBL1679884 | 0.92 | — | — | |
| Potassium Ion SCHEMBL7857699 | 0.92 | — | — | |
| Water SCHEMBL303843 | 0.92 | CA4 (0.43) | CA4FAHD1CA1MEN1LDHA | |
| Water SCHEMBL9137498 | 0.92 | CA4 (0.43) | CA4FAHD1CA1MEN1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024089420-A1 | PHOSPHATE-FREE AND CHLORINE-FREE POWDER COMPOSITION | DEMPA HOLDINGS LTD (GB) | 2024-05-02 | — | — | WO | disclosed |
| WO-2006114651-A1 | METHOD FOR TREATING EFFLUENT | PROBE INDUSTRIES LIMITED (GB) | 2006-11-02 | — | — | WO | disclosed |
| EP-0788806-A2 | Agent for releasing oxigen in an oxigen generator | Canavate Riera, Gertraud (DE) | 1997-08-13 | — | — | EP | disclosed |
| US-4171280-A | SODIUM PERCARBONATE FROM SODA ASH AND HYDROGEN PEROXIDE | THE CLOROX COMPANY (US) | 1979-10-16 | — | — | US | disclosed |