Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074806 | 0.86 | SLC6A2 (0.80) | SLC6A2SLC6A4 | |
| SCHEMBL2074980 | 0.86 | SLC6A2 (1.00) | SLC6A2SLC6A4 | |
| SCHEMBL5731601 | 0.85 | SLC6A2 (0.73) | SLC6A2SLC6A4 | |
| SCHEMBL5728552 | 0.84 | SLC6A2 (0.72) | SLC6A2SLC6A4 | |
| SCHEMBL5729578 | 0.84 | SLC6A2 (0.72) | SLC6A2SLC6A4 | |
| SCHEMBL28765777 | 0.83 | SLC6A2 (0.71) | SLC6A2SLC6A4 | |
| SCHEMBL2073496 | 0.82 | SLC6A2 (0.70) | SLC6A2SLC6A4 | |
| SCHEMBL2075091 | 0.82 | SLC6A2 (0.70) | SLC6A2SLC6A4 | |
| SCHEMBL27668131 | 0.81 | SLC6A2 (0.67) | SLC6A2SLC6A4 | |
| SCHEMBL5729863 | 0.79 | SLC6A2 (0.65) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730127-A1 | HETEROCYCLIC PHENYLAMINOPROPANOL DERIVATIVES AS MODULATORS OF THE MONOAMINE REUPTAKE FOR THE TREATMENT OF VASOMOTOR SYMPTOMS (VMS) | Wyeth, A Corporation of the State of Delaware (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005097761-A1 | HETEROCYCLIC PHENYLAMINOPROPANOL DERIVATIVES AS MODULATORS OF THE MONOAMINE REUPTAKE FOR THE TREATMENT OF VASOMOTOR SYMPTOMS (VMS) | WYETH (US) | 2005-10-20 | — | — | WO | disclosed |