Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.73 |
| ▸ | CTSD | P07339 | 4/20 | 0.33 |
| ▸ | SLC10A2 | Q12908 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731985 | 0.96 | NR1H4 (0.79) | NR1H4CTSDSLC10A2 | |
| SCHEMBL25250178 | 0.96 | NR1H4 (0.79) | NR1H4CTSDSLC10A2 | |
| SCHEMBL4732517 | 0.94 | NR1H4 (0.74) | NR1H4CTSDSLC10A2 | |
| SCHEMBL16415717 | 0.92 | NR1H4 (0.76) | NR1H4CTSDSLC10A2 | |
| SCHEMBL2687279 | 0.92 | NR1H4 (0.76) | NR1H4CTSDSLC10A2 | |
| SCHEMBL25249701 | 0.91 | NR1H4 (0.77) | NR1H4CTSDSLC10A2 | |
| SCHEMBL4615546 | 0.91 | NR1H4 (0.80) | NR1H4CTSDSLC10A2 | |
| SCHEMBL5691778 | 0.91 | NR1H4 (0.74) | NR1H4CTSDSLC10A2 | |
| SCHEMBL5142403 | 0.91 | NR1H4 (0.76) | NR1H4CTSDSLC10A2 | |
| SCHEMBL5407206 | 0.90 | NR1H4 (0.80) | NR1H4SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458673-B1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES AS AGONISTS TO HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PPAR) | ASTRAZENECA AB (SE) | 2006-09-06 | — | — | EP | claimed |