⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL6014423 | 0.98 | CYP1A2 (0.42) | — | |
| SCHEMBL1221781 | 0.94 | KCNH2 (0.48) | — | |
| SCHEMBL28018296 | 0.92 | KCNH2 (0.52) | — | |
| SCHEMBL20209685 | 0.92 | KCNH2 (0.52) | — | |
| SCHEMBL21645767 | 0.92 | KCNH2 (0.52) | — | |
| SCHEMBL21186452 | 0.92 | KCNH2 (0.52) | — | |
| Alcohol SCHEMBL22495162 | 0.88 | KCNH2 (0.44) | — | |
| SCHEMBL3834698 | 0.86 | — | — | |
| Piperazine SCHEMBL1442999 | 0.84 | KCNH2 (0.41) | — | |
| SCHEMBL22266283 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102639539-B | process for the preparation of imidazo [2,1-b ] [1,3] benzothiazole derivatives | AMBIT BIOSCIENCES CORP | 2014-12-10 | — | — | CN | claimed |
| US-11643408-B2 | N-pyridinyl acetamide derivatives as inhibitors of the WNT signaling pathway | REDX PHARMA PLC (GB) | 2023-05-09 | — | — | US | disclosed |
| WO-2023075479-A1 | NOVEL THIENO[2,3-D]PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER OR AUTOIMMUNE DISEASE COMPRISING SAME AS ACTIVE INGREDIENT | 재단법인 대구경북첨단의료산업진흥재단 | 2023-05-04 | — | — | WO | disclosed |
| US-9284332-B2 | Process for the preparation of imidazo[2,1-B][1,3]benzothiazole derivatives | AMBIT BIOSCIENCES CORPORATION (US) | 2016-03-15 | — | — | US | disclosed |
| CN-105254557-A | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RAQUALIA PHARMA INC | 2016-01-20 | — | — | CN | disclosed |
| CN-105188383-A | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG | 2015-12-23 | — | — | CN | disclosed |
| CN-105130957-A | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RAQUALIA PHARMA INC | 2015-12-09 | — | — | CN | disclosed |
| CN-102884063-B | Can be used as the azabicyclo imdazole derivatives of the replacement of TRPM8 receptor modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2015-11-25 | — | — | CN | disclosed |
| CN-104995173-A | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KIRIN CO LTD | 2015-10-21 | — | — | CN | disclosed |
| CN-102282147-B | Bicyclic pyrazolo-heterocycles | CARA THERAPEUTICS, INC. (US) | 2015-09-30 | — | — | CN | disclosed |
| CN-101501023-A | Phenyl-substituted heteroaryl derivatives and their use as antitumor agents | BOEHRINGER INGELHEIM INT (DE) | 2009-08-05 | — | — | CN | disclosed |
| CN-100999533-A | Bridged binuclear metal hydrazone complex and its synthesis method | SHANGHAI INST OPTICS & FINE ME (CN) | 2007-07-18 | — | — | CN | disclosed |
| EP-1041982-A4 | INHIBITION OF p38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS | BAYER PHARMACEUTICALS CORP (US) | 2006-06-14 | — | — | EP | disclosed |
| CN-1562985-A | Preparation method of 5-substituted-3-aminoisoxazole compound | SHANGHAI INST OPTICS & FINE ME (CN) | 2005-01-12 | — | — | CN | disclosed |
| CN-1456555-A | Isoxazole-azo-cyclohexanedione metal chelate and preparation method thereof | SHANGHAI OPTICAL PRECISION (CN) | 2003-11-19 | — | — | CN | disclosed |
| CN-1438221-A | isoxazole-azo-diketone metal azo chelate and preparation method thereof | SHANGHAI OPTICAL PREC MECHANIC (CN) | 2003-08-27 | — | — | CN | disclosed |
| CN-1093859-C | Novel indole-2,3-done-3-oxime derivatives | NEUROSEARCH AS (DK) | 2002-11-06 | — | — | CN | disclosed |
| EP-1041982-A1 | INHIBITION OF p38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS | Bayer Corporation (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999032111-A1 | INHIBITION OF p38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS | BAYER CORPORATION (US) | 1999-07-01 | — | — | WO | disclosed |
| CN-1207100-A | Novel indole-2,3-done-3-oxime derivatives | NEUROSEARCH AS (DK) | 1999-02-03 | — | — | CN | disclosed |