Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.60 |
| ▸ | ANPEP | P15144 | 2/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894528 | 1.00 | SLC6A2 (0.60) | SLC6A2TAAR1SLC6A4SLC6A3CYP2A6 | |
| SCHEMBL1280 | 1.00 | SLC6A2 (0.60) | SLC6A2TAAR1SLC6A4SLC6A3CYP2A6 | |
| SCHEMBL30913000 | 1.00 | SLC6A2 (0.60) | SLC6A2TAAR1SLC6A4SLC6A3CYP2A6 | |
| Ammonia Solution, Strong SCHEMBL5682054 | 0.98 | SLC6A2 (0.58) | SLC6A2TAAR1SLC6A4SLC6A3CYP2A6 | |
| Ammonia Solution, Strong SCHEMBL20773844 | 0.98 | SLC6A2 (0.58) | SLC6A2TAAR1SLC6A4SLC6A3CYP2A6 | |
| Hydrochloric Acid SCHEMBL10973407 | 0.98 | SLC6A2 (0.58) | SLC6A2TAAR1SLC6A4SLC6A3CYP2A6 | |
| Hydrogen Sulfide SCHEMBL28135421 | 0.98 | SLC6A2 (0.58) | SLC6A2TAAR1SLC6A4SLC6A3CYP2A6 | |
| Hydrochloric Acid SCHEMBL4752502 | 0.98 | SLC6A2 (0.58) | SLC6A2TAAR1SLC6A4SLC6A3CYP2A6 | |
| Iodide SCHEMBL29195325 | 0.98 | SLC6A2 (0.58) | SLC6A2TAAR1SLC6A4SLC6A3CYP2A6 | |
| Hydrochloric Acid SCHEMBL10976633 | 0.98 | SLC6A2 (0.58) | SLC6A2TAAR1SLC6A4SLC6A3CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110656095-B | Leucine dehydrogenase mutant and application thereof in synthesis of aromatic chiral amine | 江南大学 | 2021-05-04 | — | — | CN | claimed |
| EP-3354727-B1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2020-10-07 | — | — | EP | claimed |
| CN-110656095-A | Leucine dehydrogenase mutant and application thereof in synthesis of aromatic chiral amine | 江南大学 | 2020-01-07 | — | — | CN | claimed |
| EP-3354727-A1 | TRANSAMINASE POLYPEPTIDES | Codexis, Inc. (US) | 2018-08-01 | — | — | EP | claimed |
| EP-2385983-B1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2017-12-20 | — | — | EP | claimed |
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2012-02-16 | — | — | US | claimed |
| EP-2385983-A2 | TRANSAMINASE POLYPEPTIDES | Codexis, Inc. (US) | 2011-11-16 | — | — | EP | claimed |
| US-D646886-S1 | Tip of an umbrella | Pro Performance Sports, L.L.C. (US) | 2011-10-18 | — | — | US | claimed |
| US-20100209981-A1 | TRANSAMINASE POLYPEPTIDES | CODEXIS, INC. (US) | 2010-08-19 | — | — | US | claimed |
| WO-2010081053-A2 | TRANSAMINASE POLYPEPTIDES | CODEXIS, INC. (US) | 2010-07-15 | — | — | WO | claimed |
| WO-2007092264-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2007-08-16 | — | — | WO | claimed |
| US-20070185346-A1 | Kit for automated resolving agent selection and method thereof | VAIDYA NITEEN A | 2007-08-09 | — | — | US | claimed |
| EP-0857790-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUNDS | KANEKA CORP (JP) | 2005-08-17 | — | — | EP | claimed |
| US-20010031487-A1 | Process for producing optically active amino compounds | KANEKA CORPORATION | 2001-10-18 | — | — | US | claimed |
| US-6221638-B1 | BY STEREOSELECTIVELY CARRYING OUT AMINO GROUP TRANSFER BY ACTION OF AN (R)-FORM-SPECIFIC TRANSAMINASE IN THE CO-PRESENCE OF A KETONE (AMINO ACCEPTOR) AND AMINO COMPOUND (AMINO DONOR); YIELDS AMINO COMPOUNDS HAIVNG ARYL GROUP AT THE 1-POSITION | KANEKA CORPORATION (JP) | 2001-04-24 | — | — | US | claimed |
| EP-0987332-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUNDS | Kaneka Corporation (JP) | 2000-03-22 | — | — | EP | claimed |
| EP-0857790-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUNDS | KANEKA CORPORATION (JP) | 1998-08-12 | — | — | EP | claimed |
| EP-0396596-A1 | PROCESSES AND COMPOUNDS USEFUL FOR RESOLVING 1-METHYL-3-PHENYLPROPYLAMINE | SCHERING CORPORATION (US) | 1990-11-14 | — | — | EP | claimed |
| WO-1989005787-A2 | PROCESSES AND COMPOUNDS USEFUL FOR RESOLVING 1-METHYL-3-PHENYLPROPYLAMINE | SCHERING CORPORATION (US) | 1989-06-29 | — | — | WO | claimed |
| EP-0320898-A2 | Processes and compounds useful for resolving 1-methyl-3-phenylpropylamine | SCHERING CORPORATION (US) | 1989-06-21 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | ACKR3, KIT, C3AR1 | SLC6A2 4293/4885TAAR1 2357/4885SLC6A4 2681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.