Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5617844 | 0.88 | TLR7 (0.45) | TLR7TLR8PDE10AGAALMNA | |
| SCHEMBL5618682 | 0.88 | TLR7 (0.40) | TLR7TLR8GAALMNAMAPT | |
| SCHEMBL6053167 | 0.84 | TLR7 (0.42) | TLR7TLR8PDE10AGAALMNA | |
| SCHEMBL6053155 | 0.84 | GAA (0.39) | TLR7GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL3173290 | 0.83 | TLR7 (0.59) | TLR7TLR8LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4159656 | 0.83 | TLR7 (0.49) | TLR7TLR8GAALMNAHTT | |
| SCHEMBL5618015 | 0.82 | TLR7 (0.55) | TLR7TLR8LMNAMAPTSMN1; SMN2 | |
| SCHEMBL5618843 | 0.82 | TLR7 (0.41) | TLR7TLR8PDE10AGAALMNA | |
| SCHEMBL5669214 | 0.82 | HDAC6 (0.47) | TLR7TLR8GAALMNAMAPT | |
| SCHEMBL5349914 | 0.81 | TLR7 (0.47) | TLR7TLR8PDE10ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1686992-A2 | HYDROXYLAMINE AND OXIME SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES | 3M Innovative Properties Company (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005051324-A2 | HYDROXYLAMINE AND OXIME SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-06-09 | — | — | WO | disclosed |