SCHEMBL6053205

SCHEMBL6053205

CCCc1nc2c(N)nc3ccccc3c2n1CCCC=O

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.67
TLR8 Q9NR97 5/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5618339 0.95 TLR7 (0.75) TLR7TLR8
SCHEMBL20797231 0.91 TLR7 (0.66) TLR7TLR8
SCHEMBL6053125 0.91 TLR7 (0.79) TLR7TLR8
Acetic Acid SCHEMBL22493481 0.87 TLR7 (0.62) TLR7TLR8
SCHEMBL1950357 0.86 TLR7 (0.83) TLR7TLR8
SCHEMBL1615906 0.85 TLR7 (0.89) TLR7TLR8
SCHEMBL29182349 0.85 TLR7 (0.67) TLR7TLR8
SCHEMBL5617073 0.85 TLR7 (0.67) TLR7TLR8
SCHEMBL5618024 0.85 TLR7 (0.61) TLR7TLR8
SCHEMBL5618026 0.85 TLR7 (0.61) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1686992-A2 HYDROXYLAMINE AND OXIME SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES 3M Innovative Properties Company (US) 2006-08-09 EP disclosed
WO-2005051324-A2 HYDROXYLAMINE AND OXIME SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-06-09 WO disclosed