SCHEMBL6053248

SCHEMBL6053248

CCCCCNN=NNCCCCC

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
ALDH1A1 P00352 1/20 0.53
EPHX1 P07099 8/20 0.48
ADH1B P00325 2/20 0.42
ADH1C P00326 2/20 0.42
ADH1A P07327 2/20 0.42
ADH7 P40394 2/20 0.42
ADH4 P08319 1/20 0.42
THRB P10828 1/20 0.41
PPARA Q07869 2/20 0.37
GBA1 P04062 3/20 0.36
CASP2 P42575 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21509247 0.84 TSHR (0.43) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL14375478 0.77
SCHEMBL3911273 0.77 EPHX1 (0.50) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL10749074 0.77
SCHEMBL10893942 0.75
SCHEMBL3347455 0.75 EPHX1 (0.54) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL15958733 0.75 EPHX1 (0.48) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL17873409 0.75 EPHX1 (0.54) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL16775069 0.75
SCHEMBL177856 0.75 TSHR (0.46) TSHRALDH1A1EPHX1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140145368-A1 METHOD FOR PRODUCING FLEXOGRAPHIC PLATE ORIGINAL FOR LASER ENGRAVING FUJI-FILM CORPORATION (JP) 2014-05-29 US disclosed
EP-2623331-A1 METHOD FOR PRODUCING FLEXOGRAPHIC PLATE ORIGINAL FOR LASER ENGRAVING Toray Industries, Inc. (JP) 2013-08-07 EP disclosed
EP-1362902-B1 Pressure-sensitive adhesive and surface protecting material NITTO DENKO CORP (JP) 2006-05-31 EP disclosed
EP-0947553-B1 Process to improve release properties of polyisobutylen adhesives NITTO DENKO CORP (JP) 2004-02-18 EP disclosed
EP-1362902-A1 Pressure-sensitive adhesive and surface protecting material NITTO DENKO CORPORATION (JP) 2003-11-19 EP disclosed
EP-0839886-B1 Sheet for protecting paint film NITTO DENKO CORP (JP) 2002-05-29 EP disclosed
US-6329049-B1 Pressure-sensitive adhesive and surface protecting material NITTO DENKO CORPORATION (JP) 2001-12-11 US disclosed
US-6037054-A SUPPORT HAVING RUBBER PRESSURE SENSITIVE ADHESIVE LAYER OF ISOBUTYLENE POLYMER NITTO DENKO CORPORATION (JP) 2000-03-14 US disclosed
EP-0947553-A2 Pressure-sensitive adhesive and surface protecting material NITTO DENKO CORPORATION (JP) 1999-10-06 EP disclosed
EP-0839886-A2 Sheet for protecting paint film NITTO DENKO CORPORATION (JP) 1998-05-06 EP disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed