Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053942 | 1.00 | CYP3A4 (0.38) | CYP3A4HTTSMN1; SMN2SMYD2TAAR1 | |
| SCHEMBL6053840 | 0.83 | SMN1; SMN2 (0.42) | CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL6053841 | 0.83 | SMN1; SMN2 (0.42) | CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL6053645 | 0.79 | SMN1; SMN2 (0.39) | CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL2909392 | 0.79 | SMN1; SMN2 (0.39) | CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL6053638 | 0.79 | SMN1; SMN2 (0.39) | CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL6053581 | 0.78 | CYP3A4 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2TSHR | |
| SCHEMBL6053956 | 0.78 | CYP3A4 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2TSHR | |
| SCHEMBL6053576 | 0.78 | CYP3A4 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2TSHR | |
| SCHEMBL6053579 | 0.78 | CYP3A4 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060111324-A1 | (+)-Ttrans-isomers of (1-phosphonomethoxy-2-alkylcyclopropyl)methyl nucleoside derivatives, process for the preparation of stereoisomers thereof, and use of antiviral agents thereof | LG LIFE SCIENCES (KR) | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111324-A1 | (+)-Ttrans-isomers of (1-phosphonomethoxy-2-alkylcyclopropyl)methyl nucleoside derivatives, process for the preparation of stereoisomers thereof, and use of antiviral agents thereof | TTR, HAVCR2, PNP | CYP3A4 580/4885HTT 1430/4885SMN1; SMN2 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.