Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13046828 | 0.91 | MAP2K1 (0.87) | MAP2K1 | |
| SCHEMBL3685754 | 0.90 | MAP2K1 (1.00) | MAP2K1 | |
| SCHEMBL5138265 | 0.89 | MAP2K1 (0.87) | MAP2K1 | |
| SCHEMBL3691482 | 0.89 | MAP2K1 (0.86) | MAP2K1 | |
| SCHEMBL5138760 | 0.89 | MAP2K1 (0.79) | MAP2K1 | |
| SCHEMBL3684038 | 0.88 | MAP2K1 (1.00) | MAP2K1 | |
| SCHEMBL3687544 | 0.88 | MAP2K1 (0.86) | MAP2K1 | |
| SCHEMBL3695686 | 0.87 | MAP2K1 (1.00) | MAP2K1 | |
| SCHEMBL3694148 | 0.87 | MAP2K1 (0.85) | MAP2K1 | |
| SCHEMBL6054359 | 0.87 | MAP2K1 (0.83) | MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030112-B2 | Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-04-18 | — | — | US | claimed |
| US-7030112-B2 | Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-04-18 | — | — | US | disclosed |