Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.59 |
| ▸ | PPARD | Q03181 | 9/20 | 0.59 |
| ▸ | PPARA | Q07869 | 7/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6054804 | 0.99 | PPARG (0.60) | PPARGPPARDPPARAPTPN11TP53 | |
| SCHEMBL6054811 | 0.86 | PPARG (0.63) | PPARGPPARDPPARAPTPN11SLC6A9 | |
| SCHEMBL5989662 | 0.83 | PPARG (0.57) | PPARGPPARDPPARATP53SLC6A9 | |
| SCHEMBL5990505 | 0.82 | PPARG (0.49) | PPARGPPARDPPARATP53PTGDR2 | |
| SCHEMBL5989773 | 0.81 | PPARG (0.60) | PPARGPPARDPPARATP53SLC6A9 | |
| SCHEMBL5992887 | 0.81 | PPARG (0.63) | PPARGPPARDPPARATP53 | |
| SCHEMBL5989827 | 0.81 | PPARG (0.63) | PPARGPPARDPPARATP53 | |
| SCHEMBL5989778 | 0.81 | PPARG (0.60) | PPARGPPARDPPARATP53SLC6A9 | |
| SCHEMBL5989831 | 0.81 | PPARG (0.63) | PPARGPPARDPPARATP53 | |
| SCHEMBL5989470 | 0.81 | PPARG (0.55) | PPARGPPARDPPARATP53SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |